NEET DNA MCQs with answers Page - 1

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Q. Which enzyme is responsible for relieving supercoiling tension ahead of the replication fork?

  • (A) Helicase
  • (B) Topoisomerase
  • (C) Ligase
  • (D) Primase

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Q. In DNA replication, the lagging strand is synthesized in:

  • (A) Continuous fragments
  • (B) Okazaki fragments
  • (C) Helical loops
  • (D) Single units

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Q. Which enzyme joins Okazaki fragments?

  • (A) DNA polymerase I
  • (B) DNA ligase
  • (C) Helicase
  • (D) Primase

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Q. Which DNA polymerase in prokaryotes has proofreading activity?

  • (A) DNA polymerase I
  • (B) DNA polymerase II
  • (C) DNA polymerase III
  • (D) All of the above

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Q. The direction of DNA synthesis is:

  • (A) 3' to 5'
  • (B) 5' to 3'
  • (C) Both directions
  • (D) Random

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Q. Which statement about semiconservative replication is correct?

  • (A) Both strands are newly synthesized
  • (B) One strand is parental, one is new
  • (C) DNA is copied randomly
  • (D) Replication occurs without enzymes

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Q. Which experiment proved semiconservative replication?

  • (A) Hershey-Chase experiment
  • (B) Meselson-Stahl experiment
  • (C) Griffith experiment
  • (D) Avery-MacLeod experiment

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Q. What is the role of primase in DNA replication?

  • (A) Synthesizes DNA
  • (B) Removes primers
  • (C) Synthesizes RNA primer
  • (D) Joins fragments

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Q. Telomerase is active in:

  • (A) Somatic cells
  • (B) Germ cells
  • (C) Muscle cells
  • (D) Nerve cells

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Q. Which base pairing rule is correct?

  • (A) A-G, C-T
  • (B) A-T, C-G
  • (C) A-C, G-T
  • (D) A-U, C-G

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